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European Union

280 articles

Quality Systems

Supplier Audit Checklist for Medical Devices: ISO 13485, QMSR, and Critical Suppliers

Use this supplier audit checklist for ISO 13485 and FDA QMSR compliance, covering supplier risk, qualification, audit agendas, quality agreements, CAPA follow-up, and records.

Quality Systems

Washer-Disinfector Validation: ISO 15883, A0 and Routine Monitoring

Validate washer-disinfector equipment and cycles under ISO 15883, including IQ/OQ/PQ, A0 thermal disinfection, load configurations and routine monitoring.

EU MDR / IVDR

EU MDR Well-Established Technologies: Expanded WET Device List 2026

Guide to the 2026 EU MDR Well-Established Technology delegated acts, expanded device lists, clinical investigation exemptions, conformity assessment changes, and manufacturer steps.

Digital Health & AI

Medical Device Penetration Testing and Vulnerability Assessment

See how penetration testing, vulnerability scanning, and fuzz testing support FDA and EU MDR cybersecurity evidence for connected medical device submissions.

Digital Health & AI

Medical Device Third-Party Cybersecurity Risk Management Guide

Manage third-party cybersecurity risk for connected medical devices using FDA Section 524B, QMSR and ISO 13485 controls, SBOMs, vendor assessments, and threat modeling.

Digital Health & AI

AR/VR Medical Devices: FDA Pathways, Classification, and 2026 Guide

Guide to AR and VR medical device regulation in 2026, including FDA classification, product codes, 510(k) and De Novo routes, cleared devices, surgical navigation, therapeutic VR, and human factors.

Industry News

Regulatory Affairs Career Guide for Medical Devices: Paths, Salaries, Skills

Career guide for medical device regulatory affairs, covering role progression, salary ranges, RAC certification, core skills, and entry strategies for 2026.

Quality Systems

Agile vs Waterfall for Medical Device Software: IEC 62304 Audit Evidence

How to choose Agile, Waterfall, or hybrid medical device software development under IEC 62304, with AAMI TIR45 mapping, design controls, and auditor evidence expectations.

Risk Management

Benefit-Risk Analysis for Medical Devices: FDA, EU MDR, and ISO 14971 Decision Framework

Guide to medical device benefit-risk analysis, covering ISO 14971 residual risk, EU MDR AFAP expectations, FDA benefit-risk factors for PMA, De Novo, and 510(k), examples, and documentation.

Clinical Evidence

Clinical Equivalence Under EU MDR: Technical, Biological, and Clinical Criteria

Demonstrate clinical equivalence under EU MDR Article 61 and Annex XIV, including MDCG 2020-5 criteria, data access, gap analysis, and CE marking examples.

Quality Systems

Medical Device CMO Selection and Quality Agreement Guide

How to select a medical device CMO, define quality agreements, run supplier audits, manage change control, and align outsourced manufacturing with FDA QMSR and ISO 13485.

Clinical Evidence

Decentralized Clinical Trials for Medical Devices: FDA and Hybrid Models

How to design decentralized and hybrid clinical trials for medical devices, covering FDA guidance, remote visits, digital endpoints, wearable data, eConsent, and implementation planning.

Design Controls

Design Output Documentation for Medical Devices: Drawings, Specs, BOMs

Guide to medical device design output records, including drawings, specifications, BOMs, acceptance criteria, and traceability to design inputs under FDA QMSR and ISO 13485.

Design Controls

Design Review Evidence for Medical Devices: Agenda, Minutes, Independence

Guide to medical device design review records, covering agenda planning, meeting minutes, independent reviewers, FDA and ISO expectations, and audit-ready evidence.

Design Controls

Design Transfer to Manufacturing: DMR, Validation, and Supplier Handoff

Guide to medical device design transfer, including DMR readiness, IQ/OQ/PQ process validation, supplier qualification, production handoff, and audit-ready documentation.

Clinical Evidence

EDC Validation for Medical Device Trials: Part 11 and Data Integrity

Guide to validating EDC systems for medical device clinical trials, covering 21 CFR Part 11, audit trails, GAMP 5, IQ/OQ/PQ, ALCOA+ data integrity, sponsor duties, and FDA inspection risks.

EU MDR / IVDR

eIFU for Medical Devices: EU MDR, FDA Rules, QR Codes, and Paper IFUs

Guide to electronic IFU rules for medical devices, covering EU Regulation 2025/1234, FDA 21 CFR Part 801, website access, QR codes, paper fallback, IVDR, SaMD, and validation.

EU MDR / IVDR

EU Medical Device Registration Cost 2026: EC REP Pricing Models

Buyer-side breakdown of EU medical device registration costs in 2026, comparing EC REP hourly, registration-plus-annual, and flat-fee pricing with three-year scenarios.

Risk Management

Fault Tree Analysis for Medical Device Risk Management: FTA vs FMEA

Guide to Fault Tree Analysis under ISO 14971, including FTA vs FMEA, AND/OR gates, probability calculations, examples, and when top-down risk analysis works best.

Risk Management

Hazard Analysis Methods for Medical Devices: FMEA, FTA, PHA, HAZOP

Compare hazard analysis methods for device risk management, including FMEA, FTA, PHA, HAZOP, and use-related analysis under ISO 14971, IEC 62366, FDA, and EU MDR.