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Topic

510(k)

64 articles

Design Controls

FDA Human Factors Final Guidance 2026: Three Submission Categories and What Changed

Guide to FDA's final Human Factors guidance (effective August 1, 2026), covering Categories 1-3, Decision Point D flexibilities, and eSTAR submission rules.

Regulatory

FDA Medical Device User Fees FY 2027: MDUFA Rate Table and Budget Decisions

Complete guide to FDA medical device user fee rates for FY 2027 (MDUFA V), covering 510(k), De Novo, PMA, registration fees, small business waivers, and filing decisions.

Regulatory

FDA Medical Device Master Files (MAF): Types, LOA & Sourcing Strategy (2026)

2026 guide to FDA Medical Device Master Files (MAF under 21 CFR 814.20): functional categories, LOA workflow, MAF vs DMF vs DMR, and eSTAR integration.

Regulatory

FDA Safer Technologies Program (STeP) for Medical Devices: Complete Regulatory Guide

A comprehensive guide to the FDA Safer Technologies Program (STeP) in 2026, including eligibility criteria, safety-innovation factors, Q-Submission application steps, benefits, and TAP pilot updates.

Commercialization

Aesthetic Device Market Structure: FDA 510(k) and PMA Approvals Analysis

A data-driven map of the US aesthetic medical device market, analyzing 510(k) energy devices, the laser oligopoly, PMA implants (dermal fillers and breast implants), and recalls.

Regulatory

How to Get FDA to Tell You Which Center Will Regulate Your Product: The Pre-RFD Playbook

A comprehensive regulatory guide to FDA's Pre-Request for Designation (Pre-RFD) process for borderline and combination products under the revised November 2025 guidance.

Regulatory

FDA Medical Device Product Codes: Analysis of 7,075 Classification Codes

A data-driven analysis of the FDA Medical Device Classification Database. We parse 7,075 product codes by class, specialty panel, and submission type.

Regulatory

FDA OTC Hearing Aid Regulation: Product Codes & MAUDE Adverse Events

A comprehensive B2B regulatory guide to the FDA OTC hearing aid framework. Details product codes, 510(k) exemptions, conditions for sale, and MAUDE data.

Regulatory

FDA De Novo Database Teardown: Grants by Year, Panel, and Pathway (1997-2025)

A deep quantitative teardown of the FDA De Novo database. Analysis of annual grant trends, review timelines, advisory panel distributions, and the strategic cost-benefit of the pathway.

Regulatory

Baxter FDA Device Footprint: 510(k), PMA, Recall & Manufacturing Analysis

A comprehensive data-driven regulatory profile of Baxter's FDA clearances, PMA approvals, safety recalls, and manufacturing hubs after the Hillrom acquisition.

Regulatory

Becton Dickinson (BD) FDA Device Footprint: 510(k), PMA, Recall & Manufacturing Analysis

A comprehensive data-driven regulatory profile of Becton Dickinson's FDA clearances, PMA approvals, safety recalls, and manufacturing hubs after the 2026 Waters spin-off.

Regulatory

FDA Product Code NAY: Surgical Robotics Clearance and Recall Trends

A deep dive into FDA product code NAY (computer-assisted surgical systems) using active registry data. Learn about 510(k) clearance trends and recall root causes.

Regulatory

FDA 510(k) Clearance Trends 1995-2026: Volume Stable as Traditional Submissions Take Share

Analysis of 175,149 FDA 510(k) clearances. Volume stabilized at roughly 3,200 per year after 2007, while Traditional submissions rose from 73% to 83% as Special and Abbreviated programs declined.

Regulatory

FDA Surgical Mesh Recalls: 171 Actions and the Polymeric-Mesh MAUDE Record

Surgical mesh analysis: 171 FDA recalls, 15 Class II enforcements, and 145,000 MAUDE reports. Bard/Davol leads recalls and reports; the POP-mesh 510(k) line was pulled to Class III in 2016.

Regulatory

510(k)-Exempt in 2026: How to Check the QMSR, Registration, and UDI Duties You Owe

A 510(k) exemption removes one filing, not your compliance program. How to confirm exempt status and the QMSR, registration, and UDI duties that survive.

Regulatory

Medical Device Accessory Classification: EU MDR and FDA Pathways

How accessories are classified separately from parent devices under EU MDR Article 2(2) and FDA 513(f)(6), with examples, MDCG 2021-24 Rev.1 updates, and FDA's 2025-2026 reclassification initiative.

Regulatory

Aesthetic Device Regulation: FDA 510(k) and EU MDR for Laser, RF, and Energy Devices

How energy-based aesthetic devices — laser, RF, HIFU, IPL, cryolipolysis, and EMS — are classified and cleared by FDA and EU MDR, including special controls, Annex XVI, and 2026 compliance updates.

Quality Systems

21 CFR Part 4: Combination Product cGMP Quality Systems for Drug-Device Manufacturers

How drug-device combination product manufacturers implement quality systems under 21 CFR Part 4 — streamlined approach, QMSR update, design controls, stability, and EU MDR Article 117.

Regulatory

FDA 510(k) Fees: MDUFA V User Fee Schedule and Total Cost Breakdown

Complete guide to FDA 510(k) user fees for FY 2026 under MDUFA V, including the $26,067 standard fee, $6,517 small business fee, $11,423 establishment registration, waivers, and total project cost.

Regulatory

Medical Device Post-Approval Change Management: FDA, EU MDR, and Asian Markets (2026)

When device modifications require new regulatory submissions in the US, EU, Korea, Japan, and China — FDA special 510(k), PMA supplements, EU MDR significant changes, and Asian pathways.