MedDeviceGuideMedDeviceGuide
Topic

Biocompatibility

6 articles

Regulatory

Medical Cyanoacrylate Tissue Adhesive Sourcing & Regulatory Guide

A technical sourcing guide for medical cyanoacrylate tissue adhesives: intended use classification, 2-octyl vs n-butyl chemistry, ISO 10993, and lot release.

Regulatory

Philips CPAP Recall: PE-PUR Foam, 15 Million Devices, 561 Deaths Teardown

A detailed regulatory and quality system teardown of the Philips Respironics CPAP recall. Understand PE-PUR foam chemistry, the FDA consent decree, and MDR metrics.

Biocompatibility

NAMs for Medical Device Biocompatibility: FDA, EU & ISO 10993 Guide (2026)

NAMs for medical device biocompatibility: FDA roadmap, EU phase-out plan, ISO 10993-5/-10/-23 in vitro alternatives, chemical characterization, and regulatory strategy.

Standards & Testing

ISO 17025 Test Laboratory Selection for Medical Devices: Complete Guide

Guide to selecting ISO 17025 accredited laboratories for medical device biocompatibility, EMC, safety, and sterilization testing, including FDA ASCA scope checks and cost factors.

Biocompatibility

ISO 10993-1:2025: What Changed, Why It Matters, and How to Prepare

Practical guide to ISO 10993-1:2025 changes, including risk-based biological evaluation, the new table framework, exposure duration updates, genotoxicity, and compliance steps.

Biocompatibility

ISO 10993 Biocompatibility Testing for Medical Devices: The Complete Guide

A comprehensive guide to biological evaluation and biocompatibility testing under ISO 10993 — from categorization and test selection to chemical characterization and FDA expectations.