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Japan

16 articles

MDSAP

MDSAP in 2026: Revised Audit Approach, TGA Migration, and Post-QMSR Value

A strategic evaluation of MDSAP in 2026: analyzing the February 2026 revised audit approach, the TGA mdsap.global migration, and a post-QMSR ROI decision framework.

Digital Health & AI

Adaptive AI Medical Devices: Why an FDA PCCP Won't Update Your Model in the EU or Japan

A cross-market analysis of AI medical device change control, comparing the US FDA PCCP, Japan's IDATEN framework, and the EU's MDR and AI Act modification rules.

Regulatory

Why FDA or CE Clearances Fail to Register Aesthetic Devices in China, Korea, and Brazil

A deep regulatory analysis of aesthetic device classification and registration pathway divergence across the US, EU, China, South Korea, and Brazil, mapping sequencing strategies and all-in costs.

Regulatory

Why One FDA/CE Clearance Opens Far Fewer CGM Markets: The Global Class-Divergence Map

A comprehensive cross-market analysis of continuous glucose monitor (CGM) classification, clinical trial requirements, and reimbursement gates across the US, EU, China, Japan, and Canada.

Regulatory

Intuitive Surgical Global Regulatory Footprint: da Vinci & Ion

An FDA regulatory and commercial footprint dossier of Intuitive Surgical, mapping da Vinci and Ion clearances, product codes, and global market access.

Regulatory

Siemens Healthineers Global Regulatory Footprint: 28-Market Registry Breakdown

A comprehensive database analysis detailing Siemens Healthineers' 18,956 distinct registrations across 28 global markets, including IVD, imaging, and oncology segments.

Regulatory

Japan PMDA Device Landscape: 88,900 Approved Products and MAH Concentration

Japan's PMDA database lists ~88,900 approved medical devices held by 2,796 MAHs; the top 50 MAHs hold 40.8%, and a 2021 cluster reflects the e-IFU/UDI mandate.

Reimbursement & Market Access

Asia-Pacific Medical Device Registration: Market Comparison and Entry Strategy (2026)

Compare medical device registration across APAC markets — China, Japan, South Korea, Australia, Singapore, India, ASEAN — including timelines, fees, reliance pathways, and strategic entry order.

Regulatory

Medical Device Post-Approval Change Management: FDA, EU MDR, and Asian Markets (2026)

When device modifications require new regulatory submissions in the US, EU, Korea, Japan, and China — FDA special 510(k), PMA supplements, EU MDR significant changes, and Asian pathways.

PMDA

PMDA eCTD v4.0 for Medical Devices: Complete Transition Guide After the April 2026 Mandate

Japan's PMDA made eCTD v4.0 mandatory on April 1, 2026. Learn what changed, Module 1 expectations, device submission issues, and compliance steps.

MDSAP

MDSAP Audit Preparation: Complete Guide for Medical Device Manufacturers (2026)

Everything you need to prepare for an MDSAP audit — the 2026 updated audit approach (AU P0002.010), QMSR alignment, step-by-step preparation checklist, costs, timelines, and common nonconformities.

CE Marking

Global CE Mark Reliance Map for Medical Device Manufacturers

See where CE marking supports device approvals across 25+ markets, including full reliance, abridged review, evidence acceptance, and remaining local steps.

Reimbursement & Market Access

Japan NHI Medical Device Procurement: Reimbursement, Pricing and Market Access

Guide to Japan NHI medical device procurement, covering reimbursement pricing, STM and non-STM categories, DPC bundling, hospital tendering, and foreign supplier market access requirements.

Regulatory

Medical Device Regulatory Consulting Hourly Rates by Region (2026)

Benchmark medical device regulatory consulting rates by region and consultant tier, with cost drivers and budgeting guidance for registration projects in major markets.

Regulatory

Japan PMDA Medical Device Approval: The Complete Guide

Navigate Japan's medical device approval system — PMDA pathways, QMS requirements, MAH structure, clinical trials, reimbursement, and practical market entry guidance.

Quality Systems

MDSAP Audit: The Complete Guide to the Medical Device Single Audit Program

Everything about MDSAP — the single audit program covering FDA, Health Canada, TGA, ANVISA, and MHLW. Audit process, grading, preparation, costs, and how to pass.