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EU MDR / IVDR

126 articles

Clinical Evidence

Why Medical Device Clinical Trials Stop Early: 6,155 Terminated Studies Analysis

Analysis of 6,155 terminated medical device trials on ClinicalTrials.gov: leading failure causes, enrollment bottlenecks, and trial survival playbooks.

EU MDR / IVDR

EU MDR Article 22: Systems and Procedure Packs — Producer Obligations Guide

Complete guide to EU MDR Article 22 system and procedure pack producer obligations, the no-additional-CE-mark rule, Article 22(4) triggers, UDI, and the FDA convenience-kit comparison.

EU MDR / IVDR

EU MDR Article 97 Derogations: Legacy Device Contingency Playbook

Comprehensive guide to EU MDR Article 97 derogations, including MDCG 2022-18, Addendum 1 restrictions, national competent authority processes, and contingency planning.

Policy & Legislation

EU PFAS Restriction for Medical Devices: REACH Timelines and Derogations

How the EU REACH PFAS restriction affects medical device components, key transition timelines (5- and 12-year derogations), concentration limits, and substitution roadmaps.

Reimbursement & Market Access

EU Medical Device Procurement & TED Tenders by the Numbers (2026)

A deep quantitative teardown of EU public medical device tenders on Tenders Electronic Daily (TED). Analysis of CPV 331 notice trends, country concentrations, contract values, and top suppliers.

Regulatory

Medical Device Clinical Trials on ClinicalTrials.gov by the Numbers (2026)

A deep quantitative teardown of the ClinicalTrials.gov database for medical devices. Analysis of phase NA dominance, results-reporting compliance, sponsor classes, and decadal growth trends.

Regulatory

EUDAMED Actors by the Numbers: 48,071 Manufacturers, Importers, and ARs (2026)

A deep quantitative teardown of the EUDAMED Actor module. Analysis of role distribution, country concentration, non-EU manufacturer dependencies, and EU Authorised Representative capacity.

Regulatory

Medical Device Classification Compared: FDA vs EU MDR vs UK vs IMDRF

A comparative guide to medical device risk classification across the US (FDA), EU (MDR), UK (MHRA), and IMDRF frameworks, featuring worked examples of classification divergence.

Regulatory

EU MDR Notified Body Capacity and the 2026-2030 Certificate Expiry Cliff

Data-driven analysis of EU MDR/IVDR certificate expiry timelines, notified body capacity concentration, and manufacturer country exposure using EUDAMED and NANDO data.

EU MDR / IVDR

Custom-Made Medical Devices Under EU MDR: Annex XIII and the FDA Exemption

A complete guide to custom-made medical devices under EU MDR Annex XIII. Learn about the manufacturer statement, MDCG 2021-3, and FDA CDE comparison.

EU MDR / IVDR

EU MDR Clinical Investigation Pathway: Sponsor Obligations, EUDAMED, and Timelines

A complete guide to medical device clinical investigations under EU MDR Articles 62-82. Learn about sponsor obligations, EUDAMED submissions, and ISO 14155.

EU MDR / IVDR

European Health Data Space (EHDS) Regulation: Guide for Medical Device Manufacturers

How Regulation (EU) 2025/327 applies to medical devices and IVDs. Learn about Article 27 software components, CE marking, 2027-2031 deadlines, and GDPR alignment.

Regulatory

Medical Device Cybersecurity Compared: FDA §524B vs EU MDR/MDCG/CRA

A comprehensive regulatory comparison of medical device cybersecurity requirements under US FDA Section 524B and the EU MDR, MDCG 2019-16, and Cyber Resilience Act (CRA).

Regulatory

IVD Registration Compared: FDA 809, EU IVDR, China, Brazil & India

Side-by-side legal-text comparison of IVD registration: FDA 21 CFR Part 809, EU IVDR 2017/746, China SAMR Decree 48, Brazil RDC 830/2023, India MDR 2017 — classes, pathways, who reviews.

Digital Health & AI

EU AI Act for Medical Devices: August 2028 Deadline and MDR Dual Compliance Strategy

EU AI Act Omnibus extends medical device AI compliance to August 2, 2028. Dual MDR strategy, data governance, human oversight, tech doc integration, and preparation timeline.

Regulatory

EUDAMED After Go-Live: What the First Weeks Reveal and What to Do Next

Post-May 28 EUDAMED compliance reality check: common registration errors, data consistency traps, legacy device triage, NB certificate bottlenecks, and a six-month action plan.

Regulatory

EU MDR Post-Market Surveillance Plan: MDCG 2025-10 Practical Guide

Build a PMS plan aligned with MDCG 2025-10 guidance: proactive data collection, QMS integration, trend reporting, PMS reports vs PSURs, and custom-made device obligations.

Regulatory

EU-Switzerland MRA Update 2026: What It Means for Medical Device Market Access

How the EU-Switzerland MRA signed March 2, 2026 restores medical device mutual recognition, what changes for EU and Swiss manufacturers, swissdamed timelines, and the path to ratification.

Regulatory

Medical Device Accessory Classification: EU MDR and FDA Pathways

How accessories are classified separately from parent devices under EU MDR Article 2(2) and FDA 513(f)(6), with examples, MDCG 2021-24 Rev.1 updates, and FDA's 2025-2026 reclassification initiative.

Regulatory

Aesthetic Device Regulation: FDA 510(k) and EU MDR for Laser, RF, and Energy Devices

How energy-based aesthetic devices — laser, RF, HIFU, IPL, cryolipolysis, and EMS — are classified and cleared by FDA and EU MDR, including special controls, Annex XVI, and 2026 compliance updates.