MedDeviceGuideMedDeviceGuide
Topic

Design Controls

21 articles

Quality Systems

Medical Device Reliability Testing: HALT, HASS, ALT & MTBF

A practical guide to medical device reliability testing: HALT vs HASS vs accelerated life testing, Weibull and MTBF, Arrhenius acceleration, and where it fits in ISO 13485 design V&V.

Quality Systems

Medical Device Software Verification vs Validation: FDA and IEC 62304 Requirements

Software verification vs validation for medical devices — FDA expectations, IEC 62304 activities, documentation, traceability, and the design control process.

Design Controls

Medical Device Design Verification Test Protocol Guide

Write and execute verification test protocols with clear scope, acceptance criteria, sample size rationale, results, and FDA, EU MDR, and ISO 13485 alignment.

Design Controls

Human Factors Content for FDA Medical Device Marketing Submissions

Guide to what human factors evidence to include in FDA 510(k), De Novo, or PMA submissions, including HF categories, critical tasks, use-risk analysis, validation testing, and documentation.

Design Controls

Auto-Injector Critical-Task Matrix for Human Factors Validation

Guide to auto-injector critical-task matrices for human factors validation, including URRA inputs, dose confirmation, hold time, misfire recovery, training decay, and FDA evidence expectations.

Quality Systems

Agile vs Waterfall for Medical Device Software: IEC 62304 Audit Evidence

How to choose Agile, Waterfall, or hybrid medical device software development under IEC 62304, with AAMI TIR45 mapping, design controls, and auditor evidence expectations.

Design Controls

Design Output Documentation for Medical Devices: Drawings, Specs, BOMs

Guide to medical device design output records, including drawings, specifications, BOMs, acceptance criteria, and traceability to design inputs under FDA QMSR and ISO 13485.

Design Controls

Design Review Evidence for Medical Devices: Agenda, Minutes, Independence

Guide to medical device design review records, covering agenda planning, meeting minutes, independent reviewers, FDA and ISO expectations, and audit-ready evidence.

Design Controls

Design Transfer to Manufacturing: DMR, Validation, and Supplier Handoff

Guide to medical device design transfer, including DMR readiness, IQ/OQ/PQ process validation, supplier qualification, production handoff, and audit-ready documentation.

Risk Management

Fault Tree Analysis for Medical Device Risk Management: FTA vs FMEA

Guide to Fault Tree Analysis under ISO 14971, including FTA vs FMEA, AND/OR gates, probability calculations, examples, and when top-down risk analysis works best.

Design Controls

User Needs vs Design Inputs: Translating VOC into Medical Device Requirements

Learn how to translate VOC and user needs into verifiable design inputs with FDA QMSR, ISO 13485, traceability examples and audit-ready documentation.

Quality Systems

Engineering Change Order (ECO) for Medical Devices: Complete Process Guide

Medical device ECO guide covering ECR-to-ECN workflows, ISO 13485 design change controls, FDA QMSR expectations, risk assessment, regulatory triggers, and approvals.

Quality Systems

Medical Device Traceability Matrix: User Needs to V&V Guide

Build a medical device traceability matrix linking user needs, design inputs, risk controls, and V&V for FDA, ISO 13485, IEC 62304, and EU MDR.

Risk Management

FMEA for Medical Devices: Design, Process & Use Risk Analysis Explained

Use FMEA for medical device risk analysis, including DFMEA, PFMEA, UFMEA, ISO 14971 links, RPN scoring, step-by-step execution, and common errors.

Design Controls

Human Factors Testing for Medical Devices: FDA and IEC 62366 Guide

Plan human factors testing for devices with FDA guidance, IEC 62366-1, formative and summative studies, sample sizes, HF submission categories, and review-ready documentation.

FDA QMSR

QMSR Gap Analysis for ISO 13485 Companies: 50+ Item Checklist

Use this QMSR gap analysis checklist to map ISO 13485:2016 processes to FDA requirements for terminology, complaints, labeling, UDI, records, and action items.

Quality Systems

Medical Device Change Control: FDA and EU MDR Requirements

Guide to medical device change control for design, process, and regulatory changes, including FDA QMSR, EU MDR significant changes, Notified Body notification, and best practices.

EU MDR / IVDR

Medical Device Technical File: EU MDR Documentation Guide

Prepare EU MDR technical documentation for medical devices, including Annex II and III content, FDA DHF comparisons, STED format, ISO 13485 files, and practical assembly steps.

Standards & Testing

IEC 62366 Usability Engineering for Medical Devices: Complete Guide

Apply IEC 62366 usability engineering to medical devices, including the usability file, formative and summative evaluations, use-related risk analysis, FDA guidance, and EU MDR expectations.

Design Controls

Design Controls for Medical Devices: FDA Requirements, Process, and Implementation Guide

The complete guide to medical device design controls — FDA 21 CFR 820.30, ISO 13485 clause 7.3, the design control process, DHF requirements, traceability, and practical implementation.