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429 articles

Digital Health & AI

Medical Device Third-Party Cybersecurity Risk Management Guide

Manage third-party cybersecurity risk for connected medical devices using FDA Section 524B, QMSR and ISO 13485 controls, SBOMs, vendor assessments, and threat modeling.

Digital Health & AI

AR/VR Medical Devices: FDA Pathways, Classification, and 2026 Guide

Guide to AR and VR medical device regulation in 2026, including FDA classification, product codes, 510(k) and De Novo routes, cleared devices, surgical navigation, therapeutic VR, and human factors.

Industry News

Regulatory Affairs Career Guide for Medical Devices: Paths, Salaries, Skills

Career guide for medical device regulatory affairs, covering role progression, salary ranges, RAC certification, core skills, and entry strategies for 2026.

Quality Systems

Agile vs Waterfall for Medical Device Software: IEC 62304 Audit Evidence

How to choose Agile, Waterfall, or hybrid medical device software development under IEC 62304, with AAMI TIR45 mapping, design controls, and auditor evidence expectations.

Risk Management

Benefit-Risk Analysis for Medical Devices: FDA, EU MDR, and ISO 14971 Decision Framework

Guide to medical device benefit-risk analysis, covering ISO 14971 residual risk, EU MDR AFAP expectations, FDA benefit-risk factors for PMA, De Novo, and 510(k), examples, and documentation.

Quality Systems

Medical Device CMO Selection and Quality Agreement Guide

How to select a medical device CMO, define quality agreements, run supplier audits, manage change control, and align outsourced manufacturing with FDA QMSR and ISO 13485.

Reimbursement & Market Access

CPT, HCPCS, and ICD Coding Strategy for Medical Devices: Reimbursement Pathway Guide

Guide to CPT, HCPCS, and ICD coding strategy for medical device reimbursement, including when to seek new codes, AMA and CMS processes, payment systems, and market access planning.

Clinical Evidence

Decentralized Clinical Trials for Medical Devices: FDA and Hybrid Models

How to design decentralized and hybrid clinical trials for medical devices, covering FDA guidance, remote visits, digital endpoints, wearable data, eConsent, and implementation planning.

Design Controls

Design Output Documentation for Medical Devices: Drawings, Specs, BOMs

Guide to medical device design output records, including drawings, specifications, BOMs, acceptance criteria, and traceability to design inputs under FDA QMSR and ISO 13485.

Design Controls

Design Review Evidence for Medical Devices: Agenda, Minutes, Independence

Guide to medical device design review records, covering agenda planning, meeting minutes, independent reviewers, FDA and ISO expectations, and audit-ready evidence.

Design Controls

Design Transfer to Manufacturing: DMR, Validation, and Supplier Handoff

Guide to medical device design transfer, including DMR readiness, IQ/OQ/PQ process validation, supplier qualification, production handoff, and audit-ready documentation.

Clinical Evidence

EDC Validation for Medical Device Trials: Part 11 and Data Integrity

Guide to validating EDC systems for medical device clinical trials, covering 21 CFR Part 11, audit trails, GAMP 5, IQ/OQ/PQ, ALCOA+ data integrity, sponsor duties, and FDA inspection risks.

EU MDR / IVDR

eIFU for Medical Devices: EU MDR, FDA Rules, QR Codes, and Paper IFUs

Guide to electronic IFU rules for medical devices, covering EU Regulation 2025/1234, FDA 21 CFR Part 801, website access, QR codes, paper fallback, IVDR, SaMD, and validation.

Risk Management

Fault Tree Analysis for Medical Device Risk Management: FTA vs FMEA

Guide to Fault Tree Analysis under ISO 14971, including FTA vs FMEA, AND/OR gates, probability calculations, examples, and when top-down risk analysis works best.

Risk Management

Hazard Analysis Methods for Medical Devices: FMEA, FTA, PHA, HAZOP

Compare hazard analysis methods for device risk management, including FMEA, FTA, PHA, HAZOP, and use-related analysis under ISO 14971, IEC 62366, FDA, and EU MDR.

Risk Management

ISO/TR 24971 for Medical Devices: Practical Guidance for Applying ISO 14971

Practical guide to ISO/TR 24971:2020 for applying ISO 14971, including hazard identification, risk analysis methods, benefit-risk decisions, and cybersecurity.

Reimbursement & Market Access

Medicare NCD vs LCD for Medical Devices: Coverage Strategy Guide

Compare Medicare NCD and LCD pathways for medical devices, including evidence requirements, timelines, RAPID, Coverage with Evidence Development, MACs, and coverage strategy.

Reimbursement & Market Access

NTAP Application Guide for Medical Devices: Criteria, Timeline, and Strategy

Guide to CMS NTAP for medical devices, covering newness, cost, clinical improvement criteria, MEARIS submission, timelines, payment calculation, and pathway strategy.

Clinical Evidence

Patient-Reported Outcomes in Device Trials: PRO Validation and FDA/EU Expectations

Use PRO instruments in medical device trials with fit-for-purpose validation, endpoint planning, FDA CDRH expectations, EU MDR evidence, and submission strategy.

Risk Management

Risk Management File vs Risk Management Report: ISO 14971 Documentation Explained

Clear guide to ISO 14971 risk management files and reports, including required contents, traceability expectations, document structure, and audit findings.