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Medical Device & IVD Blog

Quality Systems

Medical Device GMP: Manufacturing Requirements, FDA Inspections, and Compliance Guide

The complete guide to Good Manufacturing Practice for medical devices — 21 CFR 820, QMSR transition, process validation, FDA inspections, Form 483 observations, and practical compliance strategies.

Regulatory

PMA vs 510(k): Differences, Requirements, and How to Choose the Right FDA Pathway

Compare FDA PMA and 510(k) pathways by evidence requirements, review timelines, costs, post-market duties, and decision criteria for US market entry.

Regulatory

China NMPA Medical Device Registration: The Complete Guide for Foreign Manufacturers

How to register medical devices with China's NMPA — classification, documentation, clinical requirements, testing, timelines, costs, and practical guidance for market entry.

Risk Management

ISO 14971 Risk Management for Medical Devices: The Complete Guide

A comprehensive guide to implementing ISO 14971 risk management for medical devices — from hazard identification through risk control to post-production monitoring.

Regulatory

Japan PMDA Medical Device Approval: The Complete Guide

Navigate Japan's medical device approval system — PMDA pathways, QMS requirements, MAH structure, clinical trials, reimbursement, and practical market entry guidance.

Regulatory

Health Canada Medical Device License: The Complete Guide

How to obtain a Medical Device License from Health Canada — classification, MDSAP requirements, MDEL, application process, fees, and practical guidance for the Canadian market.

Quality Systems

ISO 13485 Certification: Complete Guide for Medical Device Companies

Guide to ISO 13485 certification requirements, audit process, costs, timelines, registrar selection, common findings, and alignment with FDA QSR, EU MDR, and MDSAP.

Digital Health & AI

Software as a Medical Device (SaMD): The Complete Regulatory Guide

Guide to SaMD regulation covering IMDRF classification, FDA and EU MDR pathways, IEC 62304, IEC 82304-1, AI/ML change control, cybersecurity, and global frameworks.

510(k)

The Complete Guide to FDA 510(k) Submissions

Practical FDA 510(k) submission guide covering predicate selection, substantial equivalence, eSTAR formatting, user fees, common deficiencies, and first-time filing tips.

Regulatory

Brazil ANVISA Medical Device Registration: The Complete Guide

How to register medical devices with ANVISA — classification, B-GMP via MDSAP, registration pathways, documentation, fees, and practical guidance for the Brazilian market.

Clinical Evidence

Clinical Evaluation Report (CER) for Medical Devices: The Complete Guide

How to write a Clinical Evaluation Report that meets EU MDR requirements and passes Notified Body review — methodology, structure, literature search strategy, and common pitfalls.

Quality Systems

MDSAP Audit: The Complete Guide to the Medical Device Single Audit Program

Everything about MDSAP — the single audit program covering FDA, Health Canada, TGA, ANVISA, and MHLW. Audit process, grading, preparation, costs, and how to pass.

Regulatory

FDA's QSR to QMSR Transition: What Medical Device Companies Need to Know

The FDA is aligning its Quality System Regulation with ISO 13485. Here's what the QMSR final rule means for your quality management system and what you need to do to prepare.

Regulatory

South Korea MFDS Medical Device Approval: The Complete Guide

Navigate South Korea's medical device regulatory system — MFDS classification, KGMP, approval pathways, clinical requirements, and practical market entry guidance.

Regulatory

Australia TGA Medical Device Registration: The Complete Guide

How to register medical devices with Australia's TGA — classification, ARTG inclusion, sponsor requirements, MDSAP, fees, and practical guidance for the Australian market.

EU MDR / IVDR

EU MDR and IVDR: The Complete Guide to European Medical Device Regulation

Complete guide to EU MDR and IVDR for medical device and IVD manufacturers, covering classification, conformity assessment, UDI, EUDAMED, timelines, and CE marking.

Biocompatibility

ISO 10993 Biocompatibility Testing for Medical Devices: The Complete Guide

A comprehensive guide to biological evaluation and biocompatibility testing under ISO 10993 — from categorization and test selection to chemical characterization and FDA expectations.

Regulatory

FDA Medical Device Classification: Product Codes, Device Classes, and Regulatory Pathways

How FDA classifies medical devices into Class I, II, and III — product codes, regulation numbers, how to determine your device's classification, and what it means for your regulatory pathway.

Regulatory

India CDSCO Medical Device Registration: The Complete Guide

How to register medical devices with India's CDSCO — MDR 2017 classification, import licensing, BIS requirements, clinical evidence, and practical market entry guidance.

Post-Market Surveillance

Post-Market Surveillance for Medical Devices: The Complete Guide

Guide to medical device post-market surveillance, including FDA and EU MDR/IVDR requirements, PMS plans, PMCF, PSURs, vigilance, and system design.