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Quality Systems

191 articles

Quality Systems

Medical Device CMO Selection and Quality Agreement Guide

How to select a medical device CMO, define quality agreements, run supplier audits, manage change control, and align outsourced manufacturing with FDA QMSR and ISO 13485.

Design Controls

Design Output Documentation for Medical Devices: Drawings, Specs, BOMs

Guide to medical device design output records, including drawings, specifications, BOMs, acceptance criteria, and traceability to design inputs under FDA QMSR and ISO 13485.

Design Controls

Design Review Evidence for Medical Devices: Agenda, Minutes, Independence

Guide to medical device design review records, covering agenda planning, meeting minutes, independent reviewers, FDA and ISO expectations, and audit-ready evidence.

Design Controls

Design Transfer to Manufacturing: DMR, Validation, and Supplier Handoff

Guide to medical device design transfer, including DMR readiness, IQ/OQ/PQ process validation, supplier qualification, production handoff, and audit-ready documentation.

Clinical Evidence

EDC Validation for Medical Device Trials: Part 11 and Data Integrity

Guide to validating EDC systems for medical device clinical trials, covering 21 CFR Part 11, audit trails, GAMP 5, IQ/OQ/PQ, ALCOA+ data integrity, sponsor duties, and FDA inspection risks.

Risk Management

Hazard Analysis Methods for Medical Devices: FMEA, FTA, PHA, HAZOP

Compare hazard analysis methods for device risk management, including FMEA, FTA, PHA, HAZOP, and use-related analysis under ISO 14971, IEC 62366, FDA, and EU MDR.

Digital Health & AI

ISO 27001 for Medical Device Companies: Information Security Implementation Guide

Learn how medical device companies can implement ISO 27001, align ISMS controls with ISO 13485 and FDA cybersecurity expectations, and plan certification.

Risk Management

ISO/TR 24971 for Medical Devices: Practical Guidance for Applying ISO 14971

Practical guide to ISO/TR 24971:2020 for applying ISO 14971, including hazard identification, risk analysis methods, benefit-risk decisions, and cybersecurity.

Risk Management

Risk Management File vs Risk Management Report: ISO 14971 Documentation Explained

Clear guide to ISO 14971 risk management files and reports, including required contents, traceability expectations, document structure, and audit findings.

Design Controls

User Needs vs Design Inputs: Translating VOC into Medical Device Requirements

Learn how to translate VOC and user needs into verifiable design inputs with FDA QMSR, ISO 13485, traceability examples and audit-ready documentation.

Digital Health & AI

Generative AI in Medical Device Regulatory Operations

Use generative AI in device regulatory work with governance for submissions, literature review, intelligence, clinical evaluation, GxP controls, and compliance risks.

Digital Health & AI

SOUP IEC 62304 Compliance Guide for Medical Device Manufacturers

Guide to managing SOUP under IEC 62304, covering identification, risk assessment, safety classification, documentation, open-source controls, and post-market monitoring.

Regulatory

Medical Device Acronyms & Glossary: 100+ Essential Terms Every Professional Must Know

Medical device glossary with 100+ FDA, EU MDR, quality system, clinical evidence, standards, cybersecurity, and regulatory acronyms explained for professionals.

Standards & Testing

IEC 62133 Battery Safety for Medical Devices: Testing and Compliance

Meet IEC 62133 battery safety requirements for medical devices, including testing, FDA and EU MDR expectations, UN 38.3 transport, battery management, and risk controls.

Cybersecurity

HIPAA Compliance for Medical Device Companies (2026 Security Rule Update)

Manage HIPAA compliance for connected device companies, including applicability, 2026 Security Rule proposals, encryption, MFA, BAAs, IoMT risks, and FDA cybersecurity overlap.

Standards & Testing

Endotoxin and Pyrogen Testing for Medical Devices: BET Guide

Guide to medical device endotoxin and pyrogen testing, including BET methods, rFC alternatives, ISO 11737-3, USP <85>/<161>, FDA guidance, and device limits.

Regulatory

Switzerland Swissmedic Medical Device Registration Guide (2026)

How to register medical devices in Switzerland under Swissmedic: CH-REP duties, MedDO/IvDO rules, swissdamed deadlines, CE reliance, fees, and PMS obligations.

Quality Systems

Batch Records for Medical Devices: BMR, EBR, DHR, and FDA QMSR

Guide to batch manufacturing records, electronic batch records, and DHRs for medical devices, covering 21 CFR 210/211, FDA QMSR, ISO 13485, review workflows, deviations, and inspection readiness.

Sterilization & Packaging

Bioburden Testing for Medical Devices: Complete ISO 11737-1 Guide

Guide to bioburden testing under ISO 11737-1:2018, covering method validation, recovery efficiency, extraction, enumeration, dose setting, and routine monitoring for medical device sterilization.

Manufacturing

Cleanroom Standards for Medical Devices: Complete ISO 14644 Guide

Classify, design, validate, and monitor ISO 14644 cleanrooms for medical devices, including particle limits, environmental monitoring, FDA/EU GMP expectations, and 2025 updates.