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Regulatory

408 articles

Regulatory

Saudi SFDA MDS-G27: Digital Health and Wellness Device Regulation

A comprehensive guide to Saudi Arabia's SFDA MDS-G27 (2025) regulation on digital health. Understand the boundary between medical devices and wellness software.

MFDS

South Korea MFDS Registry: Risk Class, Imports, and Sponsor Concentration

A data-driven analysis of South Korea's MFDS medical device registry. Explore risk class distributions, import vs. domestic splits, and leading sponsors.

Regulatory

Swissdamed Registry Analysis: 4,554 Swiss Actors and 60,611 Device Registrations

A data-driven analysis of Swissmedic's swissdamed database. We break down actor types, risk classes, legislations, and leading CH-REPs.

Regulatory

WHO Medical Device and IVD Prequalification: The Complete Regulatory Guide

A comprehensive guide to the World Health Organization (WHO) prequalification process for medical devices and IVDs, detailing eligibility, step-by-step pathways, and key 2026 procedural updates.

Risk Management

ISO 14971 Risk-Control Traceability: How to Spot and Fix Audit Gaps

Prepare your Risk Management File for FDA or Notified Body audits. Learn to classify, locate, and remediate risk-control traceability gaps before your next QMS inspection.

Regulatory

FDA 522 Postmarket Surveillance Studies: Section 522 Order Compliance Guide

Understand FDA Section 522 postmarket surveillance orders for Class II and III devices: triggering criteria, the 30-day plan and 15-month start rules, study design, and the public 522 database.

Regulatory

Medical Device Accessibility: ADA, Section 508, and EU Accessibility Act Guide

ADA Title II/III, Section 508, WCAG 2.1 AA, and the EU Accessibility Act applied to medical devices, SaMD, patient apps, and infusion-pump screens — what it means for device design.

Regulatory

FDA 510(k) Clearance Trends 1995-2026: Volume Stable as Traditional Submissions Take Share

Analysis of 175,149 FDA 510(k) clearances. Volume stabilized at roughly 3,200 per year after 2007, while Traditional submissions rose from 73% to 83% as Special and Abbreviated programs declined.

Regulatory

FDA Medical Device Recall Concentration: Top 50 Firms Drive Over Half of All Recalls

Analysis of 58,374 FDA recall records: recall burden is concentrated. The top 50 firms drive 52% of recalls while 42% of firms recalled only once. Zimmer Biomet, Philips, Stryker, and Medtronic lead.

Regulatory

FDA Orthopedic Implant Recalls: Zimmer Biomet Leads 3,167 Hip & Knee Recall Records

FDA recall analysis: 3,167 hip, knee, and shoulder joint-replacement recalls across 70 product codes. Zimmer Biomet holds 37%, the top-10 firms 87%, and 96% are Class II 510(k) devices, not PMA.

Clinical Evidence

Investigational Device Rules Compared: FDA 21 CFR 812, EU MDR, SFDA & Health Canada

Side-by-side comparison of investigational device rules: FDA 21 CFR Part 812 IDE, EU MDR Articles 62-82, Saudi SFDA MDS-REQ 2, and Canada's Investigational Testing Authorization.

Regulatory

IVD Registration Compared: FDA 809, EU IVDR, China, Brazil & India

Side-by-side legal-text comparison of IVD registration: FDA 21 CFR Part 809, EU IVDR 2017/746, China SAMR Decree 48, Brazil RDC 830/2023, India MDR 2017 — classes, pathways, who reviews.

Post-Market Surveillance

Adverse-Event Reporting Compared: FDA 21 CFR 803, EU MDR, Brazil, Thailand & SA

Side-by-side legal-text comparison of device adverse-event reporting: FDA 21 CFR 803, EU MDR Art. 87, Brazil RDC 67/2009, Thailand MoPH, SAHPRA — triggers, timelines, who must report.

Reimbursement & Market Access

Medical Device Economic Operator Duties Compared: EU MDR, NZ, Singapore, Canada, SFDA

Compare sponsor, importer, distributor and authorized-representative duties across EU MDR Articles 11-16, New Zealand WAND, Singapore HPA, Canada MDEL and Saudi SFDA MDS-REQ 9.

Quality Systems

QMS/GMP Compared: FDA QMSR, Brazil RDC 665, Mexico NOM-241 & China

Legal-text comparison of medical device quality systems: FDA 21 CFR Part 820 (QMSR), Brazil RDC 665/2022, Mexico NOM-241-SSA1-2025, and China Order 53 — scope, certification, and audit.

Post-Market Surveillance

Recall vs FSCA Compared: FDA 21 CFR 806, EU MDR, Brazil & Thailand

Side-by-side legal-text comparison of medical device field actions: FDA 21 CFR Part 806, EU MDR FSCA/FSN, Brazil RDC 551/2021, and Thailand recall guidance — triggers, timelines, filing objects.

Labeling & UDI

UDI & Labeling Compared: FDA 801/830, EU MDR, Mexico NOM-137 & China

Legal-text comparison of medical device UDI and labeling: FDA 21 CFR Parts 801 & 830, EU MDR Article 27/Annex VI, Mexico NOM-137-SSA1-2025, and China Order 6/2014 — carriers, databases, and language.

SaMD

Software as a Medical Device (SaMD) Regulation Compared: SFDA, ANVISA, NAFDAC, PPB

Compare how Saudi SFDA MDS-G23, Brazil ANVISA RDC 657/2022, Nigeria NAFDAC and Kenya PPB regulate Software as a Medical Device — definitions, risk classes, and filing routes.

Regulatory

FDA Breast Implant Recalls: Allergan, BIA-ALCL, and the 580,000-Report MAUDE Record

Breast implant analysis: 16 Class I FDA recalls (Allergan BIOCELL), 1,380 BIA-ALCL cases, and 580,000 MAUDE reports. Capsular contracture and implant failure lead complications.

Regulatory

FDA Pacemaker and ICD Recalls: 451 Enforcement Actions and the Lead-Failure Record

Pacemaker and ICD analysis: 451 FDA enforcement actions (188 Class I) and 558,000 MAUDE reports. Boston Scientific and Medtronic lead; software and lead-impedance faults dominate Class I.