MedDeviceGuideMedDeviceGuide
Topic

Quality Systems

193 articles

EU MDR / IVDR

PSUR Under EU MDR Article 86: 2026 Periodic Safety Update Report Guide

Prepare an EU MDR Article 86 PSUR with class-based frequency, MDCG 2022-21 structure, EUDAMED submission, PMS data, and benefit-risk analysis.

Quality Systems

QA vs QC in Medical Devices: Roles, Responsibilities, and QMSR Impact

Compare QA and QC in medical device manufacturing, including process vs product focus, team roles, tools, organizational structure, and QMSR alignment.

Quality Systems

Quality Culture in Medical Devices: Leadership Practices Under FDA QMSR

Build medical device quality culture with leadership practices, ISO 13485 management responsibility, behavioral indicators, audits, and FDA QMSR expectations.

Quality Systems

Medical Device Quality Investigation Guide: Complaints, NCRs, and Audit Findings

Conduct medical device complaint, NCR, and audit finding investigations with root cause methods, CAPA, and ISO 13485, FDA 21 CFR 820, and EU MDR alignment.

Quality Systems

Quality KPIs and Metrics for Medical Devices: ISO 13485 and QMSR Guide

Build medical device quality KPIs for CAPA effectiveness, first pass yield, complaints, design controls, cost of quality, and ISO 13485 and QMSR alignment.

Quality Systems

Medical Device Quality Manual Guide: ISO 13485 Clause 4.2.2 Requirements

Write an ISO 13485:2016 medical device quality manual covering scope, procedures, QMS interactions, exclusions, FDA QMSR considerations, and template structure.

Quality Systems

Root Cause Analysis for Medical Devices: RCA Methods, Tools, and CAPA Integration

Guide to medical device root cause analysis, covering 5 Whys, fishbone diagrams, fault tree analysis, Pareto charts, CAPA links, and FDA 483 risks.

Quality Systems

Medical Device Traceability Matrix: User Needs to V&V Guide

Build a medical device traceability matrix linking user needs, design inputs, risk controls, and V&V for FDA, ISO 13485, IEC 62304, and EU MDR.

Quality Systems

Medical Device Training Management: ISO 13485, FDA QMSR & Competency

Guide to medical device training management under ISO 13485 and FDA QMSR, with competency requirements, effectiveness checks, e-training, and audit readiness.

Quality Systems

21 CFR Part 11 Compliance Guide: Electronic Records and Signatures for Medical Devices

FDA 21 CFR Part 11 guide for medical device electronic records, e-signatures, audit trails, system validation, CSA expectations, ISO 13485, and QMSR alignment.

Quality Systems

Document Control for Medical Devices: FDA, ISO 13485, and EU MDR

Guide to document control for medical device companies, covering ISO 13485 clause 4.2, FDA 21 CFR 820.40, eQMS use, change control, version control, and audit findings.

Quality Systems

Nonconformance Management for Medical Devices: NCR, Disposition, and CAPA

Medical device nonconformance management covering FDA QMSR, ISO 13485 clause 8.3, NCR writing, disposition, MRB review, CAPA escalation, and audit findings.

Regulatory

Single-Use Device Reprocessing & Remanufacturing: FDA & EU MDR Regulatory Guide (2026)

Guide to FDA and EU MDR rules for single-use device reprocessing, covering 510(k)/PMA needs, Article 17, Common Specifications, cost savings, and 2026 EU changes.

ISO 13485

ISO 13485 Certification Budget, Auditor Expectations, and Registrar Selection

Plan ISO 13485 certification budgets with 2026 cost ranges, auditor expectations, certification body selection tips, ISO 9001 differences, and FDA QMSR context.

MDSAP

MDSAP Audit Preparation: Complete Guide for Medical Device Manufacturers (2026)

Everything you need to prepare for an MDSAP audit — the 2026 updated audit approach (AU P0002.010), QMSR alignment, step-by-step preparation checklist, costs, timelines, and common nonconformities.

Risk Management

FMEA for Medical Devices: Design, Process & Use Risk Analysis Explained

Use FMEA for medical device risk analysis, including DFMEA, PFMEA, UFMEA, ISO 14971 links, RPN scoring, step-by-step execution, and common errors.

Quality Systems

Medical Device Complaint Handling: FDA, ISO 13485 & EU MDR Requirements

Guide to complaint handling for medical devices under FDA QMSR, ISO 13485, and EU MDR, covering intake, reportability, CAPA links, records, and audits.

Reimbursement & Market Access

ASEAN Device Entry: Distributor Qualification and Test Report Reuse Matrix

Six-country ASEAN matrix covering distributor licenses, QMS and warehouse requirements, vigilance setup, and where FDA or NMPA test reports may reduce retesting.

ANVISA

Brazil ANVISA Medical Device Cost Breakdown: Fees and Add-Ons (2026)

2026 Brazil ANVISA device cost guide with government fees by class, BGMP audit costs, MDSAP carve-outs, ANATEL and INMETRO add-ons, and Brazilian Registration Holder retainers.

Design Controls

Human Factors Testing for Medical Devices: FDA and IEC 62366 Guide

Plan human factors testing for devices with FDA guidance, IEC 62366-1, formative and summative studies, sample sizes, HF submission categories, and review-ready documentation.