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United States

295 articles

Sustainability & ESG

Sustainability & ESG in Medical Devices: Regulations and Best Practices

How sustainability, ESG reporting, and circular economy reshape medical device design, manufacturing, EU CSRD compliance, and lifecycle strategy.

Regulatory

510(k) Predicate Devices: How to Find, Evaluate, and Select the Right Predicate

Step-by-step guide to finding and selecting predicate devices for FDA 510(k) submissions — search strategies, substantial equivalence criteria, split predicates, and common selection mistakes.

Regulatory

FDA 510(k) Database: How to Search, Find Predicates, and Use Clearance Data

Step-by-step guide to searching the FDA 510(k) database — finding predicate devices, reading clearance summaries, using openFDA API, and leveraging 510(k) data for regulatory strategy.

Regulatory

FDA Class I Medical Devices: General Controls, Exemptions, and Regulatory Requirements

The complete guide to FDA Class I medical devices — general controls, 510(k) exemptions, GMP requirements, device listing, and what 'low risk' really means for regulatory compliance.

Regulatory

FDA Class II Medical Devices: 510(k), Special Controls, and Rules

Everything you need to know about FDA Class II medical devices — special controls, 510(k) requirements, exemptions, device examples, and how to navigate the regulatory pathway.

Regulatory

FDA Class III Medical Devices: PMA, Clinical Evidence, and Approval

The complete guide to FDA Class III medical devices — PMA applications, clinical trial requirements, pre-amendment devices, user fees, and what makes Class III the highest-risk regulatory category.

Regulatory

FDA De Novo Classification: Requirements, Process, and New Device Categories

Guide to FDA De Novo classification, including when to use the pathway, application requirements, special controls, review timelines, and how De Novo creates future predicates.

Regulatory

FDA MAUDE Database: Search and Use Medical Device Adverse Event Reports

How to search, interpret, and use the FDA MAUDE database — report types, data fields, search techniques, limitations, and practical applications for regulatory professionals.

Regulatory

FDA Product Codes: Classification, Regulation Numbers, and Exemptions

Use FDA product codes to confirm device classification, regulation numbers, 510(k) exemption status, and the likely premarket pathway.

Regulatory

PMA vs 510(k): Differences, Requirements, and How to Choose the Right FDA Pathway

Compare FDA PMA and 510(k) pathways by evidence requirements, review timelines, costs, post-market duties, and decision criteria for US market entry.

510(k)

The Complete Guide to FDA 510(k) Submissions

Practical FDA 510(k) submission guide covering predicate selection, substantial equivalence, eSTAR formatting, user fees, common deficiencies, and first-time filing tips.

Quality Systems

MDSAP Audit: The Complete Guide to the Medical Device Single Audit Program

Everything about MDSAP — the single audit program covering FDA, Health Canada, TGA, ANVISA, and MHLW. Audit process, grading, preparation, costs, and how to pass.

Regulatory

FDA's QSR to QMSR Transition: What Medical Device Companies Need to Know

The FDA is aligning its Quality System Regulation with ISO 13485. Here's what the QMSR final rule means for your quality management system and what you need to do to prepare.

Regulatory

FDA Medical Device Classification: Product Codes, Device Classes, and Regulatory Pathways

How FDA classifies medical devices into Class I, II, and III — product codes, regulation numbers, how to determine your device's classification, and what it means for your regulatory pathway.

Reimbursement & Market Access

Medical Device Reimbursement: The Complete Guide to Coding, Coverage, and Payment

How medical devices get reimbursed — coding systems, CMS coverage pathways, private payer strategy, health technology assessment, and building a reimbursement strategy from day one.